p62 app
COOH-terminal fragment of APP interacts with p62, forms
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p62 app Molecular Psychiatry 2016 TLDR It is shown that increasing brain p62 expression rescues cognitive deficits in APPPS1 mice, a widely used animal model of AD In aggrephagy, which is the selective autophagy of protein aggregates, the cargo receptors p62 and NBR1 were shown to play important roles in cargo selection Molecular Psychiatry 2016 TLDR It is shown that increasing brain p62 expression rescues cognitive deficits in APPPS1 mice, a widely used animal model of AD
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