Article The Selective Autophagy Receptor p62 Forms a Flexible

p62 app  This review focuses on the role of p62 in linking the ubiquitin–proteasome system and autophagy pathway upon ubiquitinated protein degradation  MBLI offers highly cited polyclonal and monoclonal p62 antibodies that can be used for multiple applications Fluorescent dyes or HRP conjugated

β‑asarone modulates Beclin‑1, LC3 and p62 expression to attenuate Aβ40 and Aβ42 levels in APPPS1 transgenic mice with Alzheimer's disease  p62 expression leads to reduced deposition of Aβ42, Aβ40, and amyloid precursor protein in the hippocampus of the AD animal model

Here we show that increasing brain p62 expression rescues cognitive deficits in APPPS1 mice, a widely used animal model of AD   Overproduction In humans, the loss of p62 caused damages to the central nervous system without other organs affected