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Autophagic clearance of protein aggregates requires the ubiquitin-binding receptors p62 and NBR1 The p62 protein, also known as sequestosome 1 , has a

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ufa 289 NEMO amplifies linear ubiquitylation at α-synuclein aggregates and promotes the local concentration of p62 into foci In vitro, NEMO lowers the

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